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Common Triggers of Drug Allergies
Penicillin and related antibiotics
Antibiotics containing sulfonamides (sulfa drugs)
Anticonvulsants
Aspirin, ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs)
Chemotherapy drugs
Diagnosing Drug Allergies
Skin test (accurate only for penicillin)
Drug challenge
Drug Allergy Management and Treatment
Avoid triggers.
Seek immediate medical care if symptoms worsen or multiple symptoms occur together (anaphylaxis).
Make sure that all of your health care providers, including your pharmacist, are aware of your allergy. If you have a history of anaphylaxis, wear a medical alert bracelet that lists your trigger.
Symptoms
While you may not experience allergic symptoms the first time you take a drug, your body could be producing antibodies to it. As a result, the next time you take the drug, your immune system may see it as an invader, and you’ll develop symptoms as your body releases chemicals to defend against it.

These symptoms may include:

Skin rash or hives
Itching
Wheezing or other breathing problems
Swelling
Vomiting
Feeling dizzy or light-headed
Anaphylaxis, a potentially life-threatening reaction that can impair breathing and send the body into shock; reactions may simultaneously affect two or more organ systems (for example, when there is both a rash and difficulty breathing)
Penicillin causes most allergic drug symptoms. Just because you show allergic symptoms after taking penicillin doesn’t mean that you will react to related drugs, such as amoxicillin, but it’s more likely. Also, just because you had a reaction to penicillin (or any other drug) at one time doesn’t mean you will have the same reaction in the future.

Antibiotics that contain sulfa drugs, such as Septra and Bactrim (sulfamethoxazole-trimethoprim) and Pediazole (erythromycin-sulfisoxazole), occasionally cause allergic reactions. Nonantibiotic drugs containing sulfa are very low-risk.

Diagnosing
Drug allergies can be hard to diagnose. An allergy to penicillin-type drugs is the only one that can be definitively diagnosed through a skin test. Some allergic reactions to drugs – particularly rashes, hives and asthma – can resemble certain diseases.

Your allergist will want to know the answers to these questions:

What drug do you suspect caused your reaction?
When did you start taking it, and have you stopped taking wellbutrin 150mg cheap it?
How long after you took the drug did you notice symptoms, and what did you experience?
How long did your symptoms last, and what did you do to relieve them?
What other medications, both prescription and over-the-counter, do you take?
Do you consume herbal medications or take vitamin or mineral supplements? If so, which ones?
Your allergist will also want to know whether you have had a reaction to any other drug. If you can, bring the suspected drug with you. This will help the allergist recommend alternatives as needed.

During a physical examination, your allergist will look for problems that are part of the drug reaction, along with nonallergic reasons for the reaction

Depending on the drug suspected of causing the reaction, your allergist may suggest a skin test or, in order cephalexin limited instances, a blood test. A blood test may be helpful in diagnosing a severe delayed reaction, particularly if your physician is concerned that multiple organ systems may be involved. This rare reaction is known as “drug rash with eosinophilia and systemic symptoms” or, more commonly, “DRESS syndrome.”

If a drug allergy is suspected, your allergist may also recommend an oral drug challenge, in which you will be supervised by medical staff as you take the drug suspected of triggering a reaction. (If your reaction was severe, a drug challenge may be considered too dangerous.)